You need some minimalistic requirements to use PyLucid:
If you use MySQL, you need the Python MySQLdb module v1.2.1p2 or newer. There were significant, production-related bugs in earlier versions.
If you have only a old MySQLdb Version: You can use the database backend "mysql_old" if upgrading the MySQLdb module is not immediately possible. However, this backend is deprecated, and we will not continue developing it. Please note: With the old version you will probably get encoding problems :(
Please read Enforcing MySQLdb version.